Patrick H. Willoughby, Ph.D.

Affiliations: 
2013 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Organic Chemistry
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"Patrick Willoughby"
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Thomas Robert Hoye grad student 2013 UMN
 (Strategies for the Synthesis of Bioactive Compounds: Biomimetic Approaches to the Salinosporamides and the Hexadehydro-Diels-Alder Reaction.)
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Publications

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Shen H, Xiao X, Haj MK, et al. (2018) BF3-Promoted, Carbene-like, C-H Insertion Reactions of Benzynes. Journal of the American Chemical Society
Resende GC, Alvarenga ES, Willoughby PH. (2015) Isolation and stereochemical assignment of phthalides resulting from the Diels-Alder reaction between 5-isopropoxyfuran-2(5H)-one and cyclopentadiene Journal of Molecular Structure. 1101: 212-218
Willoughby PH, Niu D, Wang T, et al. (2014) Mechanism of the reactions of alcohols with o-benzynes. Journal of the American Chemical Society. 136: 13657-65
Willoughby PH, Jansma MJ, Hoye TR. (2014) A guide to small-molecule structure assignment through computation of (¹H and ¹³C) NMR chemical shifts. Nature Protocols. 9: 643-60
Niu D, Willoughby PH, Woods BP, et al. (2013) Alkane desaturation by concerted double hydrogen atom transfer to benzyne. Nature. 501: 531-4
Baire B, Niu D, Willoughby PH, et al. (2013) Synthesis of complex benzenoids via the intermediate generation of o-benzynes through the hexadehydro-Diels-Alder reaction. Nature Protocols. 8: 501-8
Hoye TR, Baire B, Niu D, et al. (2012) The hexadehydro-Diels-Alder reaction. Nature. 490: 208-12
May AE, Willoughby PH, Hoye TR. (2008) Decarboxylative isomerization of N-Acyl-2-oxazolidinones to 2-oxazolines. The Journal of Organic Chemistry. 73: 3292-4
Burnpus JA, Willoughby PH. (2008) On the heat of formation of nitromethane Journal of Physical Organic Chemistry. 21: 747-757
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