Wei-Chieh Cheng, Ph.D.
Affiliations: | Academia Sinica, Moni Vatopediou, Taipei City, Taiwan |
Area:
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidationGoogle:
"Wei-Chieh Cheng"Mean distance: 8.92 | S | N | B | C | P |
Parents
Sign in to add mentor| Mark Joseph Kurth | grad student | 1997-2002 | UC Davis | |
| (The sulfone linker in solid -phase organic synthesis: Development of cleavage strategies for the preparation of small molecules.) | ||||
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Publications
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| Chen WA, Li HY, Sayyad A, et al. (2022) Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective α-L-Rhamnosidase Inhibitors. Chemistry, An Asian Journal |
| Cheng WC, You TY, Teo ZZ, et al. (2020) Further insights on structural modifications of muramyl dipeptides to study the human NOD2 stimulating activity. Chemistry, An Asian Journal |
| Cheng WC, Liu WJ, Hu KH, et al. (2020) Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library. Acs Combinatorial Science |
| Cheng WC, Lin CK, Li HY, et al. (2018) A combinatorial approach towards the synthesis of non-hydrolysable triazole-iduronic acid hybrid inhibitors of human α-l-iduronidase: discovery of enzyme stabilizers for the potential treatment of MPSI. Chemical Communications (Cambridge, England) |
| Wu WS, Cheng WC, Cheng TR, et al. (2018) Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase. Journal of the American Chemical Society |
| Lin CK, Hou CC, Guo YY, et al. (2016) Design and Synthesis of Orthogonally Protected d- and l-β-Hydroxyenduracididines from d-lyxono-1,4-Lactone. Organic Letters |
| Chen KT, Chen PT, Lin CK, et al. (2016) Structural Investigation of Park's Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors. Scientific Reports. 6: 31579 |
| Cheng WC, Wang JH, Li HY, et al. (2016) Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency. European Journal of Medicinal Chemistry. 123: 14-20 |
| Lin CK, Yun WY, Lin LT, et al. (2016) A concise approach to the synthesis of the unique N-mannosyl d-β-hydroxyenduracididine moiety in the mannopeptimycin series of natural products. Organic & Biomolecular Chemistry |
| Chen KT, Huang DY, Chiu CH, et al. (2015) Synthesis of Diverse N-Substituted Muramyl Dipeptide Derivatives and Their Use in a Study of Human NOD2 Stimulation Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 11984-8 |