Mark F. Springsteel, Ph.D.
Affiliations: | 2003 | University of California, Davis, Davis, CA |
Area:
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidationGoogle:
"Mark Springsteel"Mean distance: 8.92 | S | N | B | C | P |
Parents
Sign in to add mentor| Mark Joseph Kurth | grad student | 2003 | UC Davis | |
| (Synthesis of flavones, isoxazolines and related heterocycles: The search for small molecule drugs to treat cystic fibrosis.) | ||||
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Publications
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| Al-Nakkash L, Springsteel MF, Kurth MJ, et al. (2008) Activation of CFTR by UCCF-029 and genistein. Bioorganic & Medicinal Chemistry Letters. 18: 3874-7 |
| Sanderson JT, Hordijk J, Denison MS, et al. (2004) Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 70-9 |
| Springsteel MF, Galietta LJ, Ma T, et al. (2003) Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorganic & Medicinal Chemistry. 11: 4113-20 |
| Caci E, Folli C, Zegarra-Moran O, et al. (2003) CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L180-8 |
| Galietta LJ, Springsteel MF, Eda M, et al. (2001) Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. The Journal of Biological Chemistry. 276: 19723-8 |