Lori Robins, Ph.D.

Affiliations: 
2007 University of California, Davis, Davis, CA 
Area:
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidation
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"Lori Robins"
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Mark Joseph Kurth grad student 2007 UC Davis
 (Interfacing chemistry and biology: Assay development for aldose reductase inhibitors and combinatorial synthesis of diazocinones, isoxazoles and indazolo -benzoxazines.)
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Publications

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Yu GJ, Iwamoto S, Robins LI, et al. (2009) 3-(Arylthiomethyl)isoxazole-4,5-dicarboxamides: chemoselective nucleophilic chemistry and insecticidal activity. Journal of Agricultural and Food Chemistry. 57: 7422-6
Yoo CL, Yu GJ, Yang B, et al. (2008) 4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorganic & Medicinal Chemistry Letters. 18: 2610-4
Butler JD, Solano DM, Robins LI, et al. (2008) A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular Bis-heterocyclizations. The Journal of Organic Chemistry. 73: 234-40
Robins LI, Kurth MJ. (2007) 1,3,5-triazine-based mass spectral tagging of one-bead one-compound libraries. Organic Letters. 9: 171-3
Robins LI, Fettinger JC, Tinti DS, et al. (2007) Selective nucleophilic chemistry in the synthesis of 5-carbamoyl-3-sulfanylmethylisoxazole-4-carboxylic acids. Journal of Combinatorial Chemistry. 9: 139-42
Robins LI, Dixon SM, Wilson DK, et al. (2006) On-bead combinatorial techniques for the identification of selective aldose reductase inhibitors. Bioorganic & Medicinal Chemistry. 14: 7728-35
Robins LI, Carpenter RD, Fettinger JC, et al. (2006) Diazocinones: synthesis and conformational analysis. The Journal of Organic Chemistry. 71: 2480-5
Suen YF, Robins L, Yang B, et al. (2006) Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating. Bioorganic & Medicinal Chemistry Letters. 16: 537-40
Dixon S, Robins L, Elling RA, et al. (2005) Discovery of selective aldo-keto reductase ligands--an on-bead assay strategy. Bioorganic & Medicinal Chemistry Letters. 15: 2938-42
Pedemonte N, Sonawane ND, Taddei A, et al. (2005) Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Molecular Pharmacology. 67: 1797-807
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