David G. McLaren, Ph.D.

Affiliations: 
2003 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Principles of chemical separation, capillary electrophoresis, laser induced fluorescence detection, interface for separation techniques and mass spectrometry
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"David McLaren"
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David D.Y. Chen grad student 2003 UBC
 (New studies and developments in capillary electrophoresis: Advancements in complex mixture analysis and preparative operation.)
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Publications

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Li X, Parks EJ, McLaren DG, et al. (2016) An LC-MRM method for measuring intestinal triglyceride assembly using an oral stable isotope-labeled fat challenge. Bioanalysis
McLaren DG, Previs SF, Phair RD, et al. (2015) Evaluation of Cholesteryl Ester Transfer Protein Activity in vivo Under Non-Steady State Conditions: Influence of anacetrapib on High Density Lipoprotein Triglyceride Flux. Journal of Lipid Research
Whitworth KM, Rowland RR, Ewen CL, et al. (2015) Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus. Nature Biotechnology
Imbriglio JE, Shen DM, Liang R, et al. (2015) The Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitors. Journal of Medicinal Chemistry
Bojic LA, McLaren DG, Harms AC, et al. (2015) Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits. Analytical and Bioanalytical Chemistry
Song XS, Zhang J, Chen X, et al. (2015) Identification of DGAT2 Inhibitors Using Mass Spectrometry. Journal of Biomolecular Screening
Previs SF, Herath K, Castro-Perez J, et al. (2015) Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux. Methods in Enzymology. 561: 331-58
Sun S, Zhang Z, Pokrovskaia N, et al. (2015) Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors. Bioorganic & Medicinal Chemistry. 23: 455-65
Bojic LA, McLaren DG, Shah V, et al. (2014) Lipidome of atherosclerotic plaques from hypercholesterolemic rabbits. International Journal of Molecular Sciences. 15: 23283-93
Whitworth KM, Lee K, Benne JA, et al. (2014) Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos. Biology of Reproduction. 91: 78
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