Benjamin P. Duckworth, Ph.D.

Affiliations: 
2007 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
protein engineering, protein prenylation and cellular patterning
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"Benjamin Duckworth"
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Mark D. Distefano grad student 2007 UMN
 (Site -selective modification of proteins using protein farnesyltransferase.)
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Publications

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Duckworth BP, Wilson DJ, Aldrich CC. (2016) Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay. Methods in Molecular Biology (Clifton, N.J.). 1401: 53-61
Zhou W, Duckworth BP, Geraghty RJ. (2014) Fluorescent peptide sensors for tyrosylprotein sulfotransferase activity. Analytical Biochemistry. 461: 1-6
Duckworth BP, Nelson KM, Aldrich CC. (2012) Adenylating enzymes in Mycobacterium tuberculosis as drug targets. Current Topics in Medicinal Chemistry. 12: 766-96
Duckworth BP, Geders TW, Tiwari D, et al. (2011) Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis. Chemistry & Biology. 18: 1432-41
Wilson DJ, Shi C, Duckworth BP, et al. (2011) A continuous fluorescence displacement assay for BioA: an enzyme involved in biotin biosynthesis. Analytical Biochemistry. 416: 27-38
Duckworth BP, Boshoff HI, Barry CE, et al. (2011) Design of a nucleoside inhibitor of biotin protein ligase from Mycobacterium tuberculosis Collection of Czechoslovak Chemical Communications. 12: 199-203
Drake EJ, Duckworth BP, Neres J, et al. (2010) Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry. 49: 9292-305
Duckworth BP, Aldrich CC. (2010) Development of a high-throughput fluorescence polarization assay for the discovery of phosphopantetheinyl transferase inhibitors. Analytical Biochemistry. 403: 13-9
Duckworth BP, Chen Y, Wollack JW, et al. (2007) A universal method for the preparation of covalent protein-DNA conjugates for use in creating protein nanostructures. Angewandte Chemie (International Ed. in English). 46: 8819-22
Duckworth BP, Zhang Z, Hosokawa A, et al. (2007) Selective labeling of proteins by using protein farnesyltransferase. Chembiochem : a European Journal of Chemical Biology. 8: 98-105
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