Stepan Lenevich, Ph.D.

2010 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
protein engineering, protein prenylation and cellular patterning
"Stepan Lenevich"
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Mark D. Distefano grad student 2010 UMN
 (Kinetic isotope effects based analysis of the transition state structure in ypftase catalyzed geranylation reaction.)
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Lenevich S, Distefano MD. (2011) Nuclear magnetic resonance-based quantification of organic diphosphates. Analytical Biochemistry. 408: 316-20
DeGraw AJ, Palsuledesai C, Ochocki JD, et al. (2010) Evaluation of alkyne-modified isoprenoids as chemical reporters of protein prenylation. Chemical Biology & Drug Design. 76: 460-71
Rashidian M, Dozier JK, Lenevich S, et al. (2010) Selective labeling of polypeptides using protein farnesyltransferase via rapid oxime ligation. Chemical Communications (Cambridge, England). 46: 8998-9000
Hovlid ML, Edelstein RL, Henry O, et al. (2010) Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. Chemical Biology & Drug Design. 75: 51-67
Lenevich S, Xu J, Hosokawa A, et al. (2007) Transition state analysis of model and enzymatic prenylation reactions. Journal of the American Chemical Society. 129: 5796-7
Xu J, Degraw AJ, Duckworth BP, et al. (2006) Synthesis and reactivity of 6,7-dihydrogeranylazides: reagents for primary azide incorporation into peptides and subsequent staudinger ligation. Chemical Biology & Drug Design. 68: 85-96
Rose MW, Rose ND, Boggs J, et al. (2005) Evaluation of geranylazide and farnesylazide diphosphate for incorporation of prenylazides into a CAAX box-containing peptide using protein farnesyltransferase. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 529-37
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