Joshua D. Ochocki, Ph.D.

Affiliations: 
2012 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
protein engineering, protein prenylation and cellular patterning
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"Joshua Ochocki"
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Mark D. Distefano grad student 2012 UMN
 (Studies of protein prenylation in living systems: Toward the better understanding of diseases.)
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Publications

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Palsuledesai CC, Ochocki JD, Kuhns MM, et al. (2016) Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells. Acs Chemical Biology
Palsuledesai CC, Ochocki JD, Markowski TW, et al. (2014) A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins. Molecular Biosystems. 10: 1094-103
Ochocki JD, Igbavboa U, Wood WG, et al. (2014) Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis. Methods in Molecular Biology (Clifton, N.J.). 1088: 213-23
Ochocki JD, Distefano MD. (2013) Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections. Medchemcomm. 4: 476-492
Abate-Pella D, Zeliadt NA, Ochocki JD, et al. (2012) Photochemical modulation of Ras-mediated signal transduction using caged farnesyltransferase inhibitors: activation by one- and two-photon excitation. Chembiochem : a European Journal of Chemical Biology. 13: 1009-16
Ochocki JD, Mullen DG, Wattenberg EV, et al. (2011) Evaluation of a cell penetrating prenylated peptide lacking an intrinsic fluorophore via in situ click reaction. Bioorganic & Medicinal Chemistry Letters. 21: 4998-5001
DeGraw AJ, Palsuledesai C, Ochocki JD, et al. (2010) Evaluation of alkyne-modified isoprenoids as chemical reporters of protein prenylation. Chemical Biology & Drug Design. 76: 460-71
Ochocki JD, Igbavboa U, Gibson Wood W, et al. (2010) Enlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types. Chemical Biology & Drug Design. 76: 107-15
DeGraw AJ, Keiser MJ, Ochocki JD, et al. (2010) Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs. Journal of Medicinal Chemistry. 53: 2464-71
Wollack JW, Zeliadt NA, Ochocki JD, et al. (2010) Investigation of the sequence and length dependence for cell-penetrating prenylated peptides. Bioorganic & Medicinal Chemistry Letters. 20: 161-3
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