Yen-Chih Wang, Ph.D.

2014 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
protein engineering, protein prenylation and cellular patterning
"Yen-Chih Wang"
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Mark D. Distefano grad student 2014 UMN
 (Solid-phase synthesis of C-terminal peptide libraries for studying the specificity of protein farnesyltransferase.)
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Justyna K, Das R, Lorimer EL, et al. (2023) Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic Letters
Palsuledesai CC, Ochocki JD, Kuhns MM, et al. (2016) Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells. Acs Chemical Biology
Jennings BC, Danowitz AM, Wang YC, et al. (2015) Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase. Bioorganic & Medicinal Chemistry Letters
Wang YC, Distefano MD. (2015) Synthetic isoprenoid analogues for the study of prenylated proteins: Fluorescent imaging and proteomic applications. Bioorganic Chemistry. 64: 59-65
Wickramaratne S, Boldry EJ, Buehler C, et al. (2015) Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidine. The Journal of Biological Chemistry. 290: 775-87
Wang YC, Distefano MD. (2014) Synthesis and screening of peptide libraries with free C-termini. Current Topics in Peptide & Protein Research. 15: 1-23
Dozier JK, Khatwani SL, Wollack JW, et al. (2014) Engineering protein farnesyltransferase for enzymatic protein labeling applications. Bioconjugate Chemistry. 25: 1203-12
Yeo JE, Wickramaratne S, Khatwani S, et al. (2014) Synthesis of site-specific DNA-protein conjugates and their effects on DNA replication. Acs Chemical Biology. 9: 1860-8
Wang YC, Dozier JK, Beese LS, et al. (2014) Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues. Acs Chemical Biology. 9: 1726-35
Vervacke JS, Funk AL, Wang YC, et al. (2014) Diazirine-containing photoactivatable isoprenoid: synthesis and application in studies with isoprenylcysteine carboxyl methyltransferase. The Journal of Organic Chemistry. 79: 1971-8
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