Tsui-Fen Chou, Ph.D.

Affiliations: 
2006 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
development of approaches that will deliver anticancers drug, proteins and nucleic acids to cancer tissues and not normal tissues
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"Tsui-Fen Chou"
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SNBCP

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Carston R. Wagner grad student 2006 UMN
 (Histidine triad nucleotide binding proteins (Hints): Nucleoside phosphoramidases and potential regulators of aminoacyl-tRNA synthetases.)
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Publications

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Shah R, Chou TF, Maize KM, et al. (2017) Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain. Biochemical and Biophysical Research Communications
Bulfer SL, Chou TF, Arkin MR. (2016) p97 disease mutations modulate nucleotide-induced con-formation to alter protein-protein interactions. Acs Chemical Biology
Gui L, Zhang X, Li K, et al. (2016) Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes. Chemmedchem
Liu M, Lin L, Gebremariam T, et al. (2015) Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. Plos Pathogens. 11: e1004842
Zhang X, Gui L, Zhang X, et al. (2015) Altered cofactor regulation with disease-associated p97/VCP mutations. Proceedings of the National Academy of Sciences of the United States of America. 112: E1705-14
Fang CJ, Gui L, Zhang X, et al. (2015) Evaluating p97 inhibitor analogues for their domain selectivity and potency against the p97-p47 complex. Chemmedchem. 10: 52-6
Gonzalez MA, Feely SM, Speziani F, et al. (2014) A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease. Brain : a Journal of Neurology. 137: 2897-902
Chou TF, Bulfer SL, Weihl CC, et al. (2014) Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains. Journal of Molecular Biology. 426: 2886-99
Zhou X, Chou TF, Aubol BE, et al. (2013) Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 52: 3588-600
Chou TF, Li K, Frankowski KJ, et al. (2013) Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. Chemmedchem. 8: 297-312
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