Xin Zhou, Ph.D.

Affiliations: 
2010 Medicinal Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
development of approaches that will deliver anticancers drug, proteins and nucleic acids to cancer tissues and not normal tissues
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"Xin Zhou"
Mean distance: 9.13
 
SNBCP

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Carston R. Wagner grad student 2010 UMN
 (Catalytic mechanism of the hamster arylamine N-acetyltransferase 2 (NAT2) and human histidine triad nucleotide binding protein 1 (HINT1).)
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Publications

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Shah R, Maize KM, Zhou X, et al. (2017) Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry
Zhou X, Chou TF, Aubol BE, et al. (2013) Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 52: 3588-600
Zhou X, Zhang N, Liu L, et al. (2009) Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190. The Febs Journal. 276: 6928-41
Cheng J, Zhou X, Chou TF, et al. (2009) Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection. Bioorganic & Medicinal Chemistry Letters. 19: 6379-81
Chou TF, Baraniak J, Kaczmarek R, et al. (2007) Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins. Molecular Pharmaceutics. 4: 208-17
Liu F, Zhang N, Zhou X, et al. (2006) Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation. Journal of Molecular Biology. 361: 482-92
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