Donald E. Engel, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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"Donald Engel"
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William F. DeGrado grad student 2006 Penn
 (Natural protein motifs and their use in design.)
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Publications

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Bender GM, Lehmann A, Zou H, et al. (2007) De novo design of a single-chain diphenylporphyrin metalloprotein. Journal of the American Chemical Society. 129: 10732-40
Geremia S, Di Costanzo L, Randaccio L, et al. (2005) Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography. Journal of the American Chemical Society. 127: 17266-76
Engel DE, DeGrado WF. (2005) Alpha-alpha linking motifs and interhelical orientations. Proteins. 61: 325-37
Lahr SJ, Engel DE, Stayrook SE, et al. (2005) Analysis and design of turns in alpha-helical hairpins. Journal of Molecular Biology. 346: 1441-54
Senes A, Engel DE, DeGrado WF. (2004) Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Current Opinion in Structural Biology. 14: 465-79
Engel DE, DeGrado WF. (2004) Amino acid propensities are position-dependent throughout the length of alpha-helices. Journal of Molecular Biology. 337: 1195-205
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