Graham D. Clinthorne, Ph.D.
Affiliations: | 2012 | Pharmacology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Organic Chemistry, Chemical Biology, De Novo Protein DesignGoogle:
"Graham Clinthorne"Mean distance: 8.51 | S | N | B | C | P |
Parents
Sign in to add mentor| William F. DeGrado | grad student | 2012 | Penn | |
| (PHoQ: Structural and mechanistic investigations into an important bacterial sensor kinase.) | ||||
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Publications
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| Molnar KS, Bonomi M, Pellarin R, et al. (2014) Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ. Structure (London, England : 1993). 22: 1239-51 |
| Molnar KS, Goldberg SD, Sali A, et al. (2014) Multi-state modeling of the PhoQ two-component system Structure. 22: 1239-1251 |
| Lemmin T, Soto CS, Clinthorne G, et al. (2013) Assembly of the transmembrane domain of E. coli PhoQ histidine kinase: implications for signal transduction from molecular simulations. Plos Computational Biology. 9: e1002878 |
| Goldberg SD, Clinthorne GD, Goulian M, et al. (2010) Transmembrane polar interactions are required for signaling in the Escherichia coli sensor kinase PhoQ. Proceedings of the National Academy of Sciences of the United States of America. 107: 8141-6 |