Neal B. Blatt, Ph.D.

Affiliations: 
2002 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
anti-DNA autoantibody structure and function, and the identification of novel molecular targets and small molecules for the treatment of autoimmune diseases and cancer
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Gary D. Glick grad student 2002 University of Michigan
 (Characterization of a novel pro-apoptotic benzodiazepine.)
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Publications

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Cornell TT, Fleszar A, McHugh W, et al. (2012) Mitogen-activated protein kinase phosphatase 2, MKP-2, regulates early inflammation in acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L251-8
Blatt NB, Boitano AE, Lyssiotis CA, et al. (2009) Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax. Biochemical Pharmacology. 78: 966-73
Blatt NB, Boitano AE, Lyssiotis CA, et al. (2008) Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax. Free Radical Biology & Medicine. 45: 1232-42
Boitano A, Emal CD, Leonetti F, et al. (2003) Structure activity studies of a novel cytotoxic benzodiazepine. Bioorganic & Medicinal Chemistry Letters. 13: 3327-30
Blatt NB, Bednarski JJ, Warner RE, et al. (2002) Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. The Journal of Clinical Investigation. 110: 1123-32
Blatt NB, Glick GD. (2001) Signaling pathways and effector mechanisms pre-programmed cell death. Bioorganic & Medicinal Chemistry. 9: 1371-84
Blatt NB, Glick GD. (1999) Anti-DNA autoantibodies and systemic lupus erythematosus. Pharmacology & Therapeutics. 83: 125-39
Blatt NB, Bill RM, Glick GD. (1998) Characterization of a unique anti-DNA hybridoma. Hybridoma. 17: 33-9
Bill RM, Blatt NB, Glick GD. (1997) Anti-DNA autoantibodies: the other DNA-binding proteins. Bioorganic & Medicinal Chemistry. 5: 467-72
Swanson PC, Yung RL, Blatt NB, et al. (1996) Ligand recognition by murine anti-DNA autoantibodies. II. Genetic analysis and pathogenicity. The Journal of Clinical Investigation. 97: 1748-60
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