Anthony E. Boitano, Ph.D.

Affiliations: 
2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
anti-DNA autoantibody structure and function, and the identification of novel molecular targets and small molecules for the treatment of autoimmune diseases and cancer
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Gary D. Glick grad student 2005 University of Michigan
 (Mechanisms of a pro-apoptotic benzodiazepine.)
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Publications

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Gustafsson K, Rhee C, Frodermann V, et al. (2023) Clearing and replacing tissue-resident myeloid cells with an anti-CD45-antibody-drug conjugate. Blood Advances
Gustafsson K, Rhee C, Frodermann V, et al. (2023) CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer. Biorxiv : the Preprint Server For Biology
Srikanthan MA, Humbert O, Haworth KG, et al. (2020) Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning. Molecular Therapy. Methods & Clinical Development. 17: 455-464
Lanieri L, Lamothe TL, Miske O, et al. (2020) A Single Dose of a Novel Anti-Human CD117-Amanitin Antibody Drug Conjugate (ADC) Engineered for a Short Half-Life Provides Dual Conditioning and Anti-Leukemic Activity and Extends Survival Compared to Standard of Care in Multiple Preclinical Models of Acute Myeloid Leukemia (AML) Blood. 136: 47-48
Hyzy SL, Palchaudhuri R, Proctor JL, et al. (2020) Successful Allogeneic Hematopoietic Stem Cell Transplantation in Mice Mediated By Well-Tolerated Conditioning Regimens Based on CD45-Targeted Antibody Drug Conjugate: Implications for Haplo Transplantation Biology of Blood and Marrow Transplantation. 26: S160
Pearse BR, Proctor JL, McDonough SM, et al. (2020) A Non-Genotoxic Anti-CD117 Antibody Drug Conjugate (ADC) Designed for Patient Conditioning Prior to Stem Cell Transplant and HSC-Based Gene Therapy Has a Broad Therapeutic Window across Species Biology of Blood and Marrow Transplantation. 26: S35-S36
Gillard GO, Proctor JL, Brooks ML, et al. (2020) A Novel Targeted Approach to Achieve Immune System Reset: CD45-Targeted Antibody Drug Conjugates Enable Autologous HSCT and Ameliorate Disease in Preclinical Autoimmune Disease Models Biology of Blood and Marrow Transplantation. 26: S307-S308
Goncalves KA, Hyzy SL, Brooks ML, et al. (2020) High Dose Hematopoietic Stem Cell Transplantation Leads to Rapid Neural and Peripheral Disease Cross-Correction Via Robust Hematopoietic and Microglia Recovery Biology of Blood and Marrow Transplantation. 26
Wagner JE, Brunstein CG, McKenna DH, et al. (2020) Mgta-456, a Cell Therapy Utilizing Expansion of CD34+ Hematopoietic Stem Cells (HSC), Improves HLA Matching for Adult Recipients, Promotes Faster Hematopoietic Recovery and Enables Uniform Engraftment with Less Acute Graft-Vs-Host Disease (GVHD) Biology of Blood and Marrow Transplantation. 26: S205-S206
Uchida N, Tisdale JF, Donahue RE, et al. (2020) A Single Dose of CD117 Antibody Drug Conjugate Enables Hematopoietic Stem Cell Based Gene Therapy in Nonhuman Primates Biology of Blood and Marrow Transplantation. 26: S6
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