Matthew R. Birck, Ph.D.

Affiliations: 
2002 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Enzyme Mechanism of Carbohydrate Biosynthetic Pathways
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Ronald W. Woodard grad student 2002 University of Michigan
 (Evolution and inhibition of KDO 8 -P synthase.)
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Publications

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Ting LM, Shi W, Lewandowicz A, et al. (2005) Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. The Journal of Biological Chemistry. 280: 9547-54
Xu X, Wang J, Grison C, et al. (2003) Structure-based design of novel inhibitors of 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Drug Design and Discovery. 18: 91-9
Tzeng YL, Datta A, Strole C, et al. (2002) KpsF is the arabinose-5-phosphate isomerase required for 3-deoxy-D-manno-octulosonic acid biosynthesis and for both lipooligosaccharide assembly and capsular polysaccharide expression in Neisseria meningitidis. The Journal of Biological Chemistry. 277: 24103-13
Birck MR, Husain A, Sheflyan GY, et al. (2001) Studies on 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 2795-8
Birck MR, Woodard RW. (2001) Aquifex aeolicus 3-deoxy-D-manno-2-octulosonic acid 8-phosphate synthase: a new class of KDO 8-P synthase? Journal of Molecular Evolution. 52: 205-14
Birck MR, Holler TP, Woodard RW. (2000) Identification of a slow tight-binding inhibitor of 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase [20] Journal of the American Chemical Society. 122: 9334-9335
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