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Ashtamurthy S. Pawate, Ph.D.

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Membrane protein structure/function; Expression of membrane proteins from hyperthermophiles; Structure and mechanism of prokaryotic respiratory enzymes that generate a membrane potential
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"Ashtamurthy Pawate"
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Robert B. Gennis grad student 2005 UIUC
 (The AA3 type cytochrome c oxidase from Rhodobacter sphaeroides: Insights into the proton pumping mechanism from the N139D mutation in the D-channel.)

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Publications

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Jang H, Pawate AS, Bhargava R, et al. (2019) Polymeric microfluidic continuous flow mixer combined with hyperspectral FT-IR imaging for studying rapid biomolecular events. Lab On a Chip
Schieferstein JM, Pawate AS, Varel MJ, et al. (2018) X-ray transparent microfluidic platforms for membrane protein crystallization with microseeds. Lab On a Chip
Schieferstein JM, Pawate AS, Sun C, et al. (2017) X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization. Biomicrofluidics. 11: 024118
Maeki M, Yamazaki S, Pawate AS, et al. (2016) A microfluidic-based protein crystallization method in 10 micrometer-sized crystallization space Crystengcomm. 18: 7722-7727
Pawate AS, Šrajer V, Schieferstein J, et al. (2015) Towards time-resolved serial crystallography in a microfluidic device. Acta Crystallographica. Section F, Structural Biology Communications. 71: 823-30
Keswani RK, Baik J, Yeomans L, et al. (2015) Chemical Analysis of Drug Biocrystals: A Role for Counterion Transport Pathways in Intracellular Drug Disposition. Molecular Pharmaceutics. 12: 2528-36
Perry SL, Guha S, Pawate AS, et al. (2014) In situ serial Laue diffraction on a microfluidic crystallization device. Journal of Applied Crystallography. 47: 1975-1982
Khvostichenko DS, Schieferstein JM, Pawate AS, et al. (2014) X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination. Crystal Growth & Design. 14: 4886-4890
Guha S, Perry SL, Pawate AS, et al. (2012) Fabrication of X-ray compatible microfluidic platforms for protein crystallization. Sensors and Actuators. B, Chemical. 174: 1-9
Zhu J, Han H, Pawate A, et al. (2010) Decoupling mutations in the D-channel of the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that a continuous hydrogen-bonded chain of waters is essential for proton pumping. Biochemistry. 49: 4476-82
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