Matthew M. Ravn, Ph.D.

2000 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
organic chemistry and biochemistry of isoprenoid compounds
"Matthew Ravn"
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Robert M. Coates grad student 2000 UIUC
 (Stereochemistry and mechanism of the enzyme-catalyzed cyclization of geranylgeranyl diphosphate to (-)-abietadiene.)
Clayton H. Heathcock post-doc 1999-2001 UC Berkeley
 (Post Doc)
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Ravn MM, Peters RJ, Coates RM, et al. (2002) Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates. Journal of the American Chemical Society. 124: 6998-7006
Peters RJ, Ravn MM, Coates RM, et al. (2001) Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites. Journal of the American Chemical Society. 123: 8974-8
Lee HJ, Ravn MM, Coates RM. (2001) Synthesis and characterization of abietadiene, levopimaradiene, palustradiene, and neoabietadiene: Hydrocarbon precursors of the abietane diterpene resin acids Tetrahedron. 57: 6155-6167
Peters RJ, Flory JE, Jetter R, et al. (2000) Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the "pseudomature" recombinant enzyme. Biochemistry. 39: 15592-602
Ravn MM, Coates RM, Flory JE, et al. (2000) Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (-)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis. Organic Letters. 2: 573-6
Ravn MM, Jin Q, Coates RM. (2000) Synthesis of allylic isoprenoid diphosphates by S(N)2 displacement of diethyl phosphate European Journal of Organic Chemistry. 1401-1410
Ravn MM, Coates RM, Jetter R, et al. (1998) Stereospecific intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to (-)-abietadiene catalyzed by recombinant cyclase from grand fir (Abies grandis) Chemical Communications. 21-22
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