Scott J. Sauer, Ph.D.

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2011 Chemistry Duke University, Durham, NC 
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Don M. Coltart grad student 2011 Duke
 (Direct Carbon---Carbon Bond Formation Through Reductive Soft-Enolization of alpha-Halothioesters and The Total Synthesis of (+)-Mefloquine.)
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Arora J, Sauer SJ, Tarpley M, et al. (2017) Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies. Oncotarget. 8: 25848-25863
Truong N, Sauer SJ, Seraphin-Hatcher C, et al. (2016) Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of α-iodo thioesters. Organic & Biomolecular Chemistry
Allensworth JL, Sauer SJ, Lyerly HK, et al. (2013) Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism. Breast Cancer Research and Treatment. 137: 359-71
Knight JD, Sauer SJ, Coltart DM. (2011) Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones. Organic Letters. 13: 3118-21
Sauer SJ, Garnsey MR, Coltart DM. (2010) Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of α-halo thioesters and enolizable aldehydes. Journal of the American Chemical Society. 132: 13997-9
Coltart D, Sauer S, Garnsey M. (2010) Reductive Enolization in Aldol Addition to Enolizable Aldehydes Synfacts. 2010: 1388-1388
Zhou G, Yost JM, Sauer SJ, et al. (2007) A facile and efficient anti-selective four-component direct aldol addition via chemoselective thioester enolate formation. Organic Letters. 9: 4663-5
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