John M. Hatcher, Ph.D.

Affiliations: 
2011 Chemistry Duke University, Durham, NC 
 2012- Cancer Biology Dana-Farber Cancer Institute/Harvard Medical School 
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Don M. Coltart grad student 2011 Duke
 (An Umpolung Approach to the alpha-Functionalization of Ketones and Aldehydes.)
Nathanael Gray post-doc 2012-2015 Harvard Medical School/Dana-Farber Cancer Institute
Nathanael Gray research scientist 2015- Harvard Medical School/Dana-Farber Cancer Institute
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Publications

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Hatcher JM, Bahcall M, Choi HG, et al. (2015) Discovery of inhibitors that overcome the G1202R ALK resistance mutation. Journal of Medicinal Chemistry
Terai H, Tan L, Beauchamp EM, et al. (2015) Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer. Acs Chemical Biology
Hatcher JM, Zhang J, Choi HG, et al. (2015) Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 6: 584-9
Choi HG, Zhang J, Deng X, et al. (2012) Brain Penetrant LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 3: 658-662
Hatcher JM, Kohler MC, Coltart DM. (2011) Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic α-sulfenyl ketones. Organic Letters. 13: 3810-3
Hatcher JM, Coltart DM. (2010) Copper(I)-catalyzed addition of Grignard reagents to in situ-derived N-sulfonyl azoalkenes: an umpolung alkylation procedure applicable to the formation of up to three contiguous quaternary centers. Journal of the American Chemical Society. 132: 4546-7
Hatcher JM, Delea KC, Richardson JR, et al. (2008) Disruption of dopamine transport by DDT and its metabolites. Neurotoxicology. 29: 682-90
Hatcher JM, Pennell KD, Miller GW. (2008) Parkinson's disease and pesticides: a toxicological perspective. Trends in Pharmacological Sciences. 29: 322-9
Hatcher JM, Jones DP, Miller GW, et al. (2008) Neurotoxicity of Manufactured Nanoparticles Nanoscience and Nanotechnology: Environmental and Health Impacts. 405-428
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