Elizabeth J. Sacho, Ph.D.

Affiliations: 
2007 Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Scanning Force Microscopy, Biological Chemistry
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"Elizabeth Sacho"
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Dorothy A. Erie grad student 2007 UNC Chapel Hill
 (Biophysical and biochemical investigations of proteins involved in genomic maintenance and stability.)
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Publications

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Qiu R, Sakato M, Sacho EJ, et al. (2015) MutL traps MutS at a DNA mismatch. Proceedings of the National Academy of Sciences of the United States of America. 112: 10914-9
weninger k, Hao P, Yang Y, et al. (2015) Toward Adding Complexity in Single Molecule FRET Studies of DNA Mismatch Repair Biophysical Journal. 108: 69a-70a
Sacho EJ, Weninger KR. (2012) Single Molecule FRET Studies of the DNA Mismatch Repair Protein MutSα using Specific Labeling with Unnatural Amino Acids Biophysical Journal. 102: 282a
Sacho EJ, Maizels N. (2011) DNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons. The Journal of Biological Chemistry. 286: 44945-51
Chelico L, Sacho EJ, Erie DA, et al. (2008) A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV. The Journal of Biological Chemistry. 283: 13780-91
Sacho EJ, Kadyrov FA, Modrich P, et al. (2008) Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. Molecular Cell. 29: 112-21
Brar SS, Sacho EJ, Tessmer I, et al. (2008) Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. Dna Repair. 7: 77-87
Sacho EJ, Tessmer I, Diaz M, et al. (2008) Response to "Is AID a monomer in solution" Dna Repair. 7: 351-352
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