Jill Chrencik, Ph.D.
Affiliations: | 2004 | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Structural Studies of Dynamic Cellular ProcessesGoogle:
"Jill Chrencik"Mean distance: 10.32
Parents
Sign in to add mentor| Matthew R. Redinbo | grad student | 2004 | UNC Chapel Hill | |
| (Structural insights into the catalytic mechanism of human topoisomerase I and the crystal structure of the human PXR ligand binding domain with the macrolide rifampicin.) | ||||
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Publications
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| Chrencik JE, Roth CB, Terakado M, et al. (2015) Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 161: 1633-43 |
| Hall T, Shieh HS, Day JE, et al. (2012) Structure of human ADAM-8 catalytic domain complexed with batimastat. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 616-21 |
| Chrencik JE, Patny A, Leung IK, et al. (2010) Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. Journal of Molecular Biology. 400: 413-33 |
| Chrencik JE, Brooun A, Recht MI, et al. (2007) Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. The Journal of Biological Chemistry. 282: 36505-13 |
| Brooun A, Foster SA, Chrencik JE, et al. (2007) Remedial strategies in structural proteomics: Expression, purification, and crystallization of the Vav1/Rac1 complex Protein Expression and Purification. 53: 51-62 |
| Chrencik JE, Brooun A, Kraus ML, et al. (2006) Structural and biophysical characterization of the EphB4·EphrinB2 protein-protein interaction and receptor specificity Journal of Biological Chemistry. 281: 28185-28192 |
| Chrencik JE, Brooun A, Recht MI, et al. (2006) Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity. Structure (London, England : 1993). 14: 321-30 |
| Chrencik JE, Staker BL, Burgin AB, et al. (2004) Mechanisms of camptothecin resistance by human topoisomerase I mutations. Journal of Molecular Biology. 339: 773-84 |
| Chrencik JE, Burgin AB, Pommier Y, et al. (2003) Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex. The Journal of Biological Chemistry. 278: 12461-6 |