John W. Bullen, Ph.D.
Affiliations: | 2012 | Johns Hopkins University, Baltimore, MD |
Area:
O-linked glycosylationGoogle:
"John Bullen"Mean distance: 10.53 | S | N | B | C | P |
Parents
Sign in to add mentor| Gerald W. Hart | grad student | 2012 | Johns Hopkins | |
| (Dynamic direct crosstalk between two essential nutrient-sensitive processes: The O-GlcNAc and AMP-activated protein kinase systems.) | ||||
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Publications
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| Bullen JW, Tchernyshyov I, Holewinski RJ, et al. (2016) Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1. Science Signaling. 9: ra56 |
| Zhang C, Samanta D, Lu H, et al. (2016) Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA. Proceedings of the National Academy of Sciences of the United States of America |
| Lu H, Samanta D, Xiang L, et al. (2015) Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. Proceedings of the National Academy of Sciences of the United States of America. 112: E4600-9 |
| Xiang L, Gilkes DM, Hu H, et al. (2015) HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells. Oncotarget. 6: 11768-78 |
| Xiang L, Gilkes DM, Hu H, et al. (2014) Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype. Oncotarget. 5: 12509-27 |
| Bullen JW, Balsbaugh JL, Chanda D, et al. (2014) Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK). The Journal of Biological Chemistry. 289: 10592-606 |
| Copeland RJ, Bullen JW, Hart GW. (2008) Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity. American Journal of Physiology. Endocrinology and Metabolism. 295: E17-28 |
| Blüher S, Bullen J, Mantzoros CS. (2008) Altered levels of adiponectin and adiponectin receptors may underlie the effect of ciliary neurotrophic factor (CNTF) to enhance insulin sensitivity in diet-induced obese mice Hormone and Metabolic Research. 40: 225-227 |
| Alevizos I, Misra J, Bullen J, et al. (2007) Linking hepatic transcriptional changes to high-fat diet induced physiology for diabetes-prone and obese-resistant mice. Cell Cycle (Georgetown, Tex.). 6: 1631-8 |
| Bullen JW, Hart GW. (2007) The role of O‐GlcNAcylation of GLUT4 Storage Vesicle Proteins in Insulin Stimulated GLUT4 Trafficking The Faseb Journal. 21 |