Edward J. Merino, Ph.D.

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Structural and Chemical Biology of the Transcriptome
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"Edward Merino"
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Kevin M. Weeks grad student 2005 UNC Chapel Hill
 (Utilizing the 2'-ribose position for nucleic acid technologies.)
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Publications

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Zhu H, Mishra R, Yuan L, et al. (2019) Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics. Chemmedchem
Liu J, Zhu H, Premnauth G, et al. (2018) UV cell stress induces oxidative cyclization of a protective reagent for DNA damage reduction in skin explants. Free Radical Biology & Medicine
AbdulSalam SF, Gurjar PN, Zhu H, et al. (2017) Self-cyclizing Antioxidants to Prevent DNA Damage Caused by Hydroxyl Radical. Chembiochem : a European Journal of Chemical Biology
Cushion MT, Collins MS, Sesterhenn T, et al. (2016) Functional Characterization of Pneumocystis carinii Inositol Transporter 1. Mbio. 7
AbdulSalam SF, Thowfeik FS, Merino EJ. (2016) Excessive Reactive Oxygen Species and Exotic DNA Lesions as an Exploitable Liability. Biochemistry
Thowfeik FS, Abdul Salam SF, Wunderlich M, et al. (2015) A ROS-activatable agent elicits homologous recombination DNA repair and synergizes with pathway compounds. Chembiochem : a European Journal of Chemical Biology
Borland KM, AbdulSalam SF, Solivio MJ, et al. (2015) Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells. Bioorganic & Medicinal Chemistry. 23: 1869-81
Gong J, Solivio MJ, Merino EJ, et al. (2015) Developing ICP-MS/MS for the detection and determination of synthetic DNA-protein crosslink models via phosphorus and sulfur detection. Analytical and Bioanalytical Chemistry. 407: 2433-7
Vadukoot AK, AbdulSalam SF, Wunderlich M, et al. (2014) Design of a hydrogen peroxide-activatable agent that specifically targets cancer cells. Bioorganic & Medicinal Chemistry. 22: 6885-92
Amato E, Bankemper T, Kidney R, et al. (2014) Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors. Bioorganic & Medicinal Chemistry. 22: 126-34
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