Kurt H. Piepenbrink, Ph.D.
Affiliations: | 2011 | University of Notre Dame, Notre Dame, IN, United States |
Area:
molecular recognition and cellular communicationGoogle:
"Kurt Piepenbrink"Mean distance: 9.54 | S | N | B | C | P |
Parents
Sign in to add mentor| Brian M. Baker | grad student | 2011 | Notre Dame | |
| (Understanding the energetic basis for T-cell receptor recognition.) | ||||
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Publications
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| Vila T, Kong EF, Ibrahim A, et al. (2019) quorum-sensing molecule farnesol modulates staphyloxanthin production and activates the thiol-based oxidative-stress response in . Virulence. 10: 625-642 |
| Pierce BG, Boucher EN, Piepenbrink KH, et al. (2017) Structure-Based Design of Hepatitis C Virus Vaccines that Elicit Neutralizing Antibody Responses to a Conserved Epitope. Journal of Virology |
| Wang Y, Singh NK, Spear TT, et al. (2017) How an alloreactive T-cell receptor achieves peptide and MHC specificity. Proceedings of the National Academy of Sciences of the United States of America |
| Riley TP, Ayres CM, Hellman LM, et al. (2016) A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. Protein Engineering, Design & Selection : Peds |
| Piao W, Ru LW, Piepenbrink KH, et al. (2013) Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. Proceedings of the National Academy of Sciences of the United States of America. 110: 19036-41 |
| Smith SN, Sommermeyer D, Piepenbrink KH, et al. (2013) Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes. Journal of Molecular Biology. 425: 4496-507 |
| Piepenbrink KH, Blevins SJ, Scott DR, et al. (2013) The basis for limited specificity and MHC restriction in a T cell receptor interface. Nature Communications. 4: 1948 |
| Baker BM, Piepenbrink KH, Blevins SJ. (2013) T Cell Receptor Specificity, Cross-Reactivity, and MHC Restriction are Inextricably Linked and Result from Cooperative Engagement of the Composite Peptide/MHC Surface Biophysical Journal. 104: 403a |
| Aggen DH, Chervin AS, Schmitt TM, et al. (2012) Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains. Gene Therapy. 19: 365-74 |
| Scott DR, Borbulevych OY, Piepenbrink KH, et al. (2011) Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism. Journal of Molecular Biology. 414: 385-400 |