Louis E. Metzger, Ph.D.

Affiliations: 
2010 Biochemistry Duke University, Durham, NC 
Area:
lipid biochemistry
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"Louis Metzger"
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Christian R.H. Raetz grad student 2010 Duke
 (Characterization of peripheral-membrane enzymes required for lipid A biosynthesis in gram-negative bacteria.)
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Publications

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Wei JR, Richie DL, Mostafavi M, et al. (2017) LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates. Msphere. 2
Dovala D, Rath CM, Hu Q, et al. (2016) Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism. Proceedings of the National Academy of Sciences of the United States of America
Richie DL, Takeoka KT, Bojkovic J, et al. (2016) Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606. Plos One. 11: e0160918
Metzger LE, Lee JK, Finer-Moore JS, et al. (2012) LpxI structures reveal how a lipid A precursor is synthesized. Nature Structural & Molecular Biology. 19: 1132-8
Metzger LE, Lee JK, Finer-Moore JS, et al. (2012) LpxI: A Novel Phosphosaccharolipid Hydrolase Biophysical Journal. 102: 303a
Metzger LE, Raetz CR. (2010) An alternative route for UDP-diacylglucosamine hydrolysis in bacterial lipid A biosynthesis. Biochemistry. 49: 6715-26
Metzger LE, Raetz CR. (2009) Purification and characterization of the lipid A disaccharide synthase (LpxB) from Escherichia coli, a peripheral membrane protein. Biochemistry. 48: 11559-71
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