Zhengqiang Wang, Ph.D.

Affiliations: 
2003 Wayne State University, Detroit, MI, United States 
Area:
Higher Order Cycloadditions
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"Zhengqiang Wang"
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SNBCP

Parents

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James H. Rigby grad student 2003 Wayne State
 (I. Novel reactions of vinyl isocyanates and vinyl ketenes with nucleophilic carbenes. II. Studies towards the total synthesis of camptothecin, nothapoditine B and plicamine.)
Robert Vince research scientist UMN

Children

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Vekataramana Sirivolu post-doc UMN
Yue-Lei Chen post-doc 2009-2010 UMN
Sanjeev Vernekar research scientist UMN
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Publications

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Xie J, Wang Z. (2021) Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs? An and DMPK assessment. Acta Pharmaceutica Sinica. B. 11: 1607-1616
Wang L, Edwards TC, Sahani RL, et al. (2021) Metal binding 6-arylthio-3-hydroxypyrimidine-2,4-diones inhibited human cytomegalovirus by targeting the pUL89 endonuclease of the terminase complex. European Journal of Medicinal Chemistry. 222: 113640
Sun Q, Levy RM, Kirby KA, et al. (2021) Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation. Viruses. 13
Senaweera S, Du H, Zhang H, et al. (2021) Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches. Viruses. 13
Sahani RL, Diana-Rivero R, Vernekar SKV, et al. (2021) Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74. Viruses. 13
Wang L, Casey MC, Vernekar SKV, et al. (2021) Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability. Acta Pharmaceutica Sinica. B. 11: 810-822
Senaweera S, He T, Cui H, et al. (2021) 4-Benzylideneisoquinoline-1,3(,)-diones as tyrosyl DNA phosphodiesterase 2 (TDP2) inhibitors. Medicinal Chemistry Research : An International Journal For Rapid Communications On Design and Mechanisms of Action of Biologically Active Agents. 30: 371-386
Oshima K, Zhao J, Pérez-Durán P, et al. (2020) Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia. Nature Cancer. 1: 1113-1127
Adam ABM, Wan X, Wang Z. (2020) Energy Efficiency Maximization for Multi-Cell Multi-Carrier NOMA Networks. Sensors (Basel, Switzerland). 20
Wang L, Casey MC, Vernekar SKV, et al. (2020) Novel HIV-1 capsid-targeting small molecules of the PF74 binding site. European Journal of Medicinal Chemistry. 204: 112626
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