James M. Hochrein, Ph.D.

2007 University of New Mexico, Albuquerque, NM, United States 
Bioanalytical chemistry, mass spectrometry, hydrogen/deuterium exchange
"James Hochrein"
Mean distance: 10.98


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John R. Engen grad student 2007 Univ. of New Mexico
 (Probing the conformational changes in Hck, a Src -family kinase, using hydrogen exchange mass spectrometry.)
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Wales TE, Hochrein JM, Morgan CR, et al. (2015) Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor. Biochemistry. 54: 6382-91
Engen JR, Wales TE, Hochrein JM, et al. (2008) Structure and dynamic regulation of Src-family kinases. Cellular and Molecular Life Sciences : Cmls. 65: 3058-73
Meyn MA, Wilson MB, Abdi FA, et al. (2006) Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity. The Journal of Biological Chemistry. 281: 30907-16
Hochrein JM, Wales TE, Lerner EC, et al. (2006) Conformational features of the full-length HIV and SIV Nef proteins determined by mass spectrometry. Biochemistry. 45: 7733-9
Hochrein JM, Lerner EC, Schiavone AP, et al. (2006) An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry. Protein Science : a Publication of the Protein Society. 15: 65-73
Lerner EC, Trible RP, Schiavone AP, et al. (2005) Activation of the Src family kinase Hck without SH3-linker release. The Journal of Biological Chemistry. 280: 40832-7
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