Kristi A. Leonard, Ph.D.

Affiliations: 
2000 State University of New York, Buffalo, Buffalo, NY, United States 
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Michael R. Detty grad student 2000 SUNY Buffalo
 (The design and synthesis of novel chalcogenopyrylium dyes as agents for photodynamic therapy.)
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Publications

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Gege C, Albers M, Kinzel O, et al. (2020) Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt. Bioorganic & Medicinal Chemistry Letters. 30: 127205
Steeneck C, Gege C, Kinzel O, et al. (2020) Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. Bioorganic & Medicinal Chemistry Letters. 30: 127174
Tanis VM, Venkatesan H, Cummings MD, et al. (2019) 3-Substituted Quinolines as RORγt Inverse Agonists. Bioorganic & Medicinal Chemistry Letters
Gege C, Cummings MD, Albers M, et al. (2018) Identification and biological evaluation of thiazole-based inverse agonists of RORγt. Bioorganic & Medicinal Chemistry Letters
Barbay JK, Cummings MD, Abad M, et al. (2017) 6-Substituted quinolines as RORγt inverse agonists. Bioorganic & Medicinal Chemistry Letters
Shook BC, Chakravarty D, Barbay JK, et al. (2013) Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 2688-91
Subasinghe NL, Khalil E, Travins JM, et al. (2012) Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s. Bioorganic & Medicinal Chemistry Letters. 22: 5303-7
Shook BC, Rassnick S, Wallace N, et al. (2012) Design and characterization of optimized adenosine A₂A/A₁ receptor antagonists for the treatment of Parkinson's disease. Journal of Medicinal Chemistry. 55: 1402-17
Raboisson P, Manthey CL, Chaikin M, et al. (2006) Novel potent and selective αvβ3αvβ5 integrin dual antagonists with reduced binding affinity for human serum albumin European Journal of Medicinal Chemistry. 41: 847-861
Leonard KA, Hall JP, Nelen MI, et al. (2000) A selenopyrylium photosensitizer for photodynamic therapy related in structure to the antitumor agent AA1 with potent in vivo activity and no long-term skin photosensitization. Journal of Medicinal Chemistry. 43: 4488-98
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