Younghwa Na, Ph.D.

Affiliations: 
2000 University of Houston, Houston, TX, United States 
Area:
biological mechanisms of therapeutic agents
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"Younghwa Na"
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Harold Kohn grad student 2000 University of Houston
 (Syntheses and evaluation of novel mitomycins.)
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Publications

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Park S, Hwang SY, Shin J, et al. (2019) A chromenone analog as an ATP-competitive, DNA non-intercalative topoisomerase II catalytic inhibitor with preferences toward the alpha isoform. Chemical Communications (Cambridge, England)
Cho H, Hee Seo S, Na Y, et al. (2018) The synthesis and anticancer activities of chiral epoxy-substituted chromone analogs. Bioorganic Chemistry. 84: 347-354
An H, Lee S, Lee JM, et al. (2018) Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy. Journal of Medicinal Chemistry
Moon H, Yoon H, Lim C, et al. (2018) Asymmetric Synthesis of (-)-6-Desmethyl-Fluvirucinine A₁ via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions. Molecules (Basel, Switzerland). 23
Choi B, Choi SK, Park YN, et al. (2017) Sensitization of lung cancer cells by altered dimerization of HSP27. Oncotarget. 8: 105372-105382
Hwang SY, Kwak SY, Kwon Y, et al. (2017) Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27. European Journal of Medicinal Chemistry. 139: 892-900
Choi SK, Mun GI, Choi E, et al. (2017) The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection. Journal of Natural Products
Jeon KH, Yu HB, Kwak SY, et al. (2016) Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones. Bioorganic & Medicinal Chemistry
Park S, Hong E, Kwak SY, et al. (2016) Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors. European Journal of Medicinal Chemistry. 123: 211-225
Kim JH, Jung YJ, Choi B, et al. (2016) Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules. Oncotarget
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