Andrew P. Brogan, Ph.D.

Affiliations: 
2004 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
biological mechanisms of therapeutic agents
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Harold Kohn grad student 2004 UNC Chapel Hill
 (Novel inhibitors of the transcription termination factor rho and mechanistic studies of rho function.)
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Publications

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Brogan AP, Widger WR, Bensadek D, et al. (2005) Development of a technique to determine bicyclomycin-rho binding and stoichiometry by isothermal titration calorimetry and mass spectrometry. Journal of the American Chemical Society. 127: 2741-51
Brogan AP, Verghese J, Widger WR, et al. (2005) Bismuth-dithiol inhibition of the Escherichia coli rho transcription termination factor. Journal of Inorganic Biochemistry. 99: 841-51
Skordalakes E, Brogan AP, Park BS, et al. (2005) Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin. Structure (London, England : 1993). 13: 99-109
Brogan AP, Widger WR, Kohn H. (2003) Bicyclomycin fluorescent probes: synthesis and biochemical, biophysical, and biological properties. The Journal of Organic Chemistry. 68: 5575-87
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