Kimberly M. Lovell, Ph.D.
Affiliations: | Scripps Research Institute Florida |
Area:
pharmacologyGoogle:
"Kimberly Lovell"Mean distance: 11.14 | S | N | B | C | P |
Parents
Sign in to add mentor| Thomas E. Prisinzano | grad student | 2011 | University of Kansas | |
| (The synthesis and pharmacological evaluation of salvinorin A analogues as opioid receptor probes.) | ||||
| Laura M. Bohn | post-doc | 2012- | Scripps Research Institute Florida | |
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Publications
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| Ma H, Brust T, Frankowski KJ, et al. (2022) Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance. Acs Chemical Neuroscience. 13: 1315-1332 |
| Kennedy NM, Schmid CL, Ross NC, et al. (2018) Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry |
| Schmid CL, Kennedy NM, Ross NC, et al. (2017) Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 171: 1165-1175.e13 |
| Lovell KM, Frankowski KJ, Stahl EL, et al. (2017) Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias". Acs Chemical Neuroscience |
| Scarry SM, Lovell KM, Frankowski KJ, et al. (2016) Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-alpha]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence. The Journal of Organic Chemistry |
| Zhou L, Stahl EL, Lovell KM, et al. (2015) Characterization of kappa opioid receptor mediated, dynorphin-stimulated [(35)S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting. Neuropharmacology |
| Lovell KM, Frankowski KJ, Stahl EL, et al. (2015) Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias. Acs Chemical Neuroscience |
| Frankowski KJ, Slauson SR, Lovell KM, et al. (2015) Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. Bioorganic & Medicinal Chemistry. 23: 3948-56 |
| Caspers MJ, Williams TD, Lovell KM, et al. (2013) LC-MS/MS quantification of salvinorin A from biological fluids. Analytical Methods : Advancing Methods and Applications. 5 |
| Zhou L, Lovell KM, Frankowski KJ, et al. (2013) Development of functionally selective, small molecule agonists at kappa opioid receptors. The Journal of Biological Chemistry. 288: 36703-16 |