Kimberly M. Lovell, Ph.D.

Affiliations: 
Scripps Research Institute Florida 
Area:
pharmacology
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"Kimberly Lovell"
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Parents

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Thomas E. Prisinzano grad student 2011 University of Kansas
 (The synthesis and pharmacological evaluation of salvinorin A analogues as opioid receptor probes.)
Laura M. Bohn post-doc 2012- Scripps Research Institute Florida
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Publications

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Kennedy NM, Schmid CL, Ross NC, et al. (2018) Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry
Schmid CL, Kennedy NM, Ross NC, et al. (2017) Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 171: 1165-1175.e13
Lovell KM, Frankowski KJ, Stahl EL, et al. (2017) Correction to "Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias". Acs Chemical Neuroscience
Scarry SM, Lovell KM, Frankowski KJ, et al. (2016) Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-alpha]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence. The Journal of Organic Chemistry
Zhou L, Stahl EL, Lovell KM, et al. (2015) Characterization of kappa opioid receptor mediated, dynorphin-stimulated [(35)S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting. Neuropharmacology
Lovell KM, Frankowski KJ, Stahl EL, et al. (2015) Structure-Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling Bias. Acs Chemical Neuroscience
Frankowski KJ, Slauson SR, Lovell KM, et al. (2015) Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. Bioorganic & Medicinal Chemistry. 23: 3948-56
Raphemot R, Rouhier MF, Swale DR, et al. (2014) Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. Plos One. 9: e110772
Caspers MJ, Williams TD, Lovell KM, et al. (2013) LC-MS/MS quantification of salvinorin A from biological fluids. Analytical Methods : Advancing Methods and Applications. 5
Zhou L, Lovell KM, Frankowski KJ, et al. (2013) Development of functionally selective, small molecule agonists at kappa opioid receptors. The Journal of Biological Chemistry. 288: 36703-16
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