Inna Goreshnik, Ph.D.

Affiliations: 
2011 University of Washington, Seattle, Seattle, WA 
Area:
Chemical Biology of Signal Transduction
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SNBCP

Parents

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Dustin James Maly grad student 2011 University of Washington
 (Engineering of a Small Molecule-Regulated Switch for Studying Signaling Enzymes.)
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Publications

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An L, Said M, Tran L, et al. (2023) De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles. Biorxiv : the Preprint Server For Biology
Lee GR, Pellock SJ, Norn C, et al. (2023) Small-molecule binding and sensing with a designed protein family. Biorxiv : the Preprint Server For Biology
Huang B, Abedi M, Ahn G, et al. (2023) Designed Endocytosis-Triggering Proteins mediate Targeted Degradation. Biorxiv : the Preprint Server For Biology
Bennett NR, Coventry B, Goreshnik I, et al. (2023) Improving de novo protein binder design with deep learning. Nature Communications. 14: 2625
Wu K, Bai H, Chang YT, et al. (2023) De novo design of modular peptide-binding proteins by superhelical matching. Nature
Hunt AC, Case JB, Park YJ, et al. (2022) Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Science Translational Medicine. eabn1252
Cao L, Coventry B, Goreshnik I, et al. (2022) Design of protein binding proteins from target structure alone. Nature
Hunt AC, Case JB, Park YJ, et al. (2021) Multivalent designed proteins protect against SARS-CoV-2 variants of concern. Biorxiv : the Preprint Server For Biology
Sahtoe DD, Coscia A, Mustafaoglu N, et al. (2021) Transferrin receptor targeting by de novo sheet extension. Proceedings of the National Academy of Sciences of the United States of America. 118
Cao L, Goreshnik I, Coventry B, et al. (2020) De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science (New York, N.Y.)
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