Sanjay B. Hari, Ph.D.

Affiliations: 
2013 Chemistry University of Washington, Seattle, Seattle, WA 
Area:
Chemical Biology of Signal Transduction
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"Sanjay Hari"
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Parents

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Thomas J. Magliery research assistant 2006-2008 Ohio State
Dustin James Maly grad student 2009-2013 University of Washington
 (Investigating Inactive Conformations of Protein Kinases.)
Robert T. Sauer post-doc 2014- MIT
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Publications

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Hari SB, Morehouse JP, Baker TA, et al. (2022) FtsH degrades kinetically stable dimers of cyclopropane fatty acid synthase via an internal degron. Molecular Microbiology
Tang Y, Meister TR, Walczak M, et al. (2019) A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites. Plos Biology. 17: e3000136
Hari SB, Grant RA, Sauer RT. (2018) Structural and Functional Analysis of E. coli Cyclopropane Fatty Acid Synthase. Structure (London, England : 1993)
Amberg-Johnson K, Hari SB, Ganesan SM, et al. (2017) Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens. Elife. 6
Amberg-Johnson K, Hari SB, Ganesan SM, et al. (2017) Author response: Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens Elife
Hari SB, Sauer RT. (2016) The AAA+ FtsH Protease Degrades an ssrA-Tagged Model Protein in the Inner Membrane of Escherichia coli. Biochemistry
Feldman HC, Tong M, Wang L, et al. (2016) Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands. Acs Chemical Biology
Ghosh R, Wang L, Wang ES, et al. (2014) Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. Cell. 158: 534-48
Hari SB, Merritt EA, Maly DJ. (2014) Conformation-selective ATP-competitive inhibitors control regulatory interactions and noncatalytic functions of mitogen-activated protein kinases. Chemistry & Biology. 21: 628-35
Hari SB, Perera BG, Ranjitkar P, et al. (2013) Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src. Acs Chemical Biology. 8: 2734-43
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