Lukas Werner

2009- Brock University, Saint Catharines, Ontario, Canada 
"Lukas Werner"
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Machara A, Werner L, Leisch H, et al. (2015) Synthesis of Naltrexone and (R)-Methylnaltrexone from Oripavine via Direct Oxidation of Its Quaternary Salts Synlett. 26: 2101-2108
Giacometti RD, Duchek J, Werner L, et al. (2013) Heteroatom analogues of hydrocodone: synthesis and biological activity. The Journal of Organic Chemistry. 78: 2914-25
Werner L, Wernerova M, MacHara A, et al. (2012) Unexpected N-demethylation of oxymorphone and oxycodone N-oxides mediated by the burgess reagent: Direct synthesis of naltrexone, naloxone, and other antagonists from oxymorphone Advanced Synthesis and Catalysis. 354: 2706-2712
MacHara A, Werner L, Endoma-Arias MA, et al. (2012) Improved synthesis of buprenorphine from thebaine and/or oripavine via palladium-catalyzed N-demethylation/acylation and/or concomitant O-demethylation Advanced Synthesis and Catalysis. 354: 613-626
Werner L, Machara A, Sullivan B, et al. (2011) Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics. The Journal of Organic Chemistry. 76: 10050-67
Werner L, Machara A, Adams DR, et al. (2011) Synthesis of buprenorphine from oripavine via N-demethylation of oripavine quaternary salts. The Journal of Organic Chemistry. 76: 4628-34
Hudlicky JR, Werner L, Semak V, et al. (2011) Dauben-Michno oxidative transposition of allylic cyanohydrins - Enantiomeric switch of (-)-carvone to (+)-carvone Canadian Journal of Chemistry. 89: 535-543
Werner L, Machara A, Adams DR, et al. (2011) Synthesis of Buprenorphine Synfacts. 2011: 817-817
Parkan K, Werner L, Lövyová Z, et al. (2010) An approach to stereoselective preparation of 3-C-glycosylated D- and L-glucals. Carbohydrate Research. 345: 352-62
Werner L, Hudlicky JR, Wernerova M, et al. (2010) Synthesis of 1,2- and 1,4-amino alcohols from 1,3-dienes via oxazines. Rearrangements of 1,4-amino alcohol derivatives to oxazolines Tetrahedron. 66: 3761-3769
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