Danese M. Joiner, Ph.D.

Affiliations: 
2010 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Molecular and Cellular Biomechanics, Organ and Whole Body Biomechanics, Tissue Engineering and Regenerative Medicine
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"Danese Joiner"
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Steven A. Goldstein grad student 2010 University of Michigan
 (The effect of age on bone and its response to mechanical stimulation.)
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Publications

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Kamiya N, Atsawasuwan P, Joiner DM, et al. (2020) Controversy of physiological vs. pharmacological effects of BMP signaling: Constitutive activation of BMP type IA receptor-dependent signaling in osteoblast lineage enhances bone formation and resorption, not affecting net bone mass. Bone. 115513
Zhang H, Zhang Y, Terajima M, et al. (2020) Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes in mice depending on anatomical location of the bones. Bone. 115402
Schumacher CA, Joiner DM, Less KD, et al. (2016) Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6. Bone Research. 4: 15042
Joiner DM, Tayim RJ, McElderry JD, et al. (2014) Aged male rats regenerate cortical bone with reduced osteocyte density and reduced secretion of nitric oxide after mechanical stimulation. Calcified Tissue International. 94: 484-94
Joiner D, Less K, VanWieren E, et al. (2013) Mice with global deletion of mitogen inducible gene 6 display rapid and severe cartilage and subchondral bone damage after ligament and meniscus injury Osteoarthritis and Cartilage. 21: S13-S14
Joiner DM, Tayim RJ, Kadado A, et al. (2012) Bone marrow stromal cells from aged male rats have delayed mineralization and reduced response to mechanical stimulation through nitric oxide and ERK1/2 signaling during osteogenic differentiation. Biogerontology. 13: 467-78
Pelton K, Krieder J, Joiner D, et al. (2012) Hypercholesterolemia promotes an osteoporotic phenotype. The American Journal of Pathology. 181: 928-36
Joiner DM, Daley ELH, Goldstein SA. (2009) The effects of the inhibition of connexin 43 on pre-osteoblasts and their response to mechanical stimulation Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 409-410
MacDonald BT, Joiner DM, Oyserman SM, et al. (2007) Bone mass is inversely proportional to Dkk1 levels in mice. Bone. 41: 331-9
Joiner DM, MacDonald BT, He X, et al. (2007) Reduction of the WnT inhibitor Dkk1 correlates with improved bone mechanical and morphological properties in mice Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 859-860
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