Mark E. Harder

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
membrane structure, DNA interactions, protein folding
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"Mark Harder"
Mean distance: 6635.5
 

Parents

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David F. Silbert grad student 1968-1975 Washington University
 (Thesis: Fatty Acid Biosynthetic Mutants in E. Coli.)
Leonard J. Banaszak post-doc 1975-1978 Washington University
 (Small angle X-ray Scattering of inner and outer membranes of E. Coli.)
George W. Brady post-doc 1978-1981 N.Y. State Department of Health
 (SAXS of Ca-Mg ATPase in lipid bilayers.)
W. Curtis Johnson research scientist 1986-1989 Oregon State
 (Binding of divalent metal cations to Z-DNA)
Michael I. Schimerlik research scientist 1984-2007 Oregon State
 ('84-'86:Muscarinic Receptor. 1996-2007: Protein unfolding thermodynamics, Global data analysis.)

Collaborators

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Thomas P. Ellen collaborator 2006-2006 NYU
 (Co-author, Circular Dichroism of metal binding to heterochromatin.)
BETA: Related publications

Publications

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Ellen TP, Kluz T, Harder ME, et al. (2009) Heterochromatinization as a potential mechanism of nickel-induced carcinogenesis. Biochemistry. 48: 4626-32
Harder ME, Malencik DA, Yan X, et al. (2009) Equilibrium unfolding of the retinoid X receptor ligand binding domain and characterization of an unfolding intermediate. Biophysical Chemistry. 141: 1-10
Harder ME, Deinzer ML, Leid ME, et al. (2004) Global analysis of three-state protein unfolding data. Protein Science : a Publication of the Protein Society. 13: 2207-22
Maier CS, Yan X, Harder ME, et al. (2000) Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric analysis of the recombinant human macrophage colony stimulating factor beta and derivatives. Journal of the American Society For Mass Spectrometry. 11: 237-43
Brady GW, Fein DB, Meissner G, et al. (1982) Liquid diffraction analysis of sarcoplasmic reticulum. II. Solvent electron contrast variation. Biophysical Journal. 37: 637-45
Brady GW, Fein DB, Harder ME, et al. (1981) A liquid diffraction analysis of sarcoplasmic reticulum. I. Compositional variation. Biophysical Journal. 34: 13-34
Harder ME, Banaszak LJ. (1979) Small angle x-ray scattering from the inner and outer membranes from Escherichia coli. Biochimica Et Biophysica Acta. 552: 89-102
Harder ME, Ladenson RC, Schimmel SD, et al. (1974) Mutants of Escherichia coli with temperature-sensitive malonyl coenzyme A-acyl carrier protein transacylase. The Journal of Biological Chemistry. 249: 7468-75
Silbert DF, Cronan JE, Beacham IR, et al. (1974) Proceedings: Genetic engineering of membrane lipid. Federation Proceedings. 33: 1725-32
Harder ME, Beacham IR, Cronan JE, et al. (1972) Temperature-sensitive mutants of Escherichia coli requiring saturated and unsaturated fatty acids for growth: isolation and properties. Proceedings of the National Academy of Sciences of the United States of America. 69: 3105-9
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