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Rafal M. Pielak, Ph.D.

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
 2011-2013 University of California, Berkeley, Berkeley, CA, United States 
Area:
NMR, single molecule biophysics, skin biochemistry, sensors
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"Rafal M Pielak"
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Parents

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James J. Chou grad student 2010 Harvard
 (The influenza M2 proton channel: Mechanisms of proton conductance, inhibition and resistance.)
Jay T. Groves post-doc 2011-2013 UC Berkeley

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Publications

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Pielak RM, O'Donoghue GP, Lin JJ, et al. (2017) Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Proceedings of the National Academy of Sciences of the United States of America
Coyle MP, O'Donoghue GP, Pielak RM, et al. (2014) Investigation of TCR Triggering Mechanism with Membrane Anchored Fab' Fragments Biophysical Journal. 106: 520a
Lin JJ, O'Donoghue GP, Pielak RM, et al. (2014) Single Molecule Observation of TCR Signaling Complexes in Living T Cells Biophysical Journal. 106: 519a
O'Donoghue GP, Pielak R, Lin JJ, et al. (2014) Direct, Single Molecule, Cell-by-Cell Observation of Molecular Kinetics and Thermodynamics in Early Lymphocyte Signaling Biophysical Journal. 106: 19a
O'Donoghue GP, Pielak RM, Smoligovets AA, et al. (2013) Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells. Elife. 2: e00778
O'Donoghue GP, Pielak RM, Smoligovets AA, et al. (2013) Author response: Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells Elife
Pielak R, O'Donoghue G, Smoligovets A, et al. (2013) Single Molecule Measurements of TCR:MHC Binding Kinetics in Living Primary T Cells Biophysical Journal. 104: 575a
O'Donoghue GP, Pielak RM, Smoligovets AA, et al. (2013) Direct, Single Molecule Observation of Early Lymphocyte Signaling Biophysical Journal. 104: 574a
Pielak RM, Oxenoid K, Chou JJ. (2011) Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses. Structure (London, England : 1993). 19: 1655-63
Pielak RM, Chou JJ. (2011) Influenza M2 proton channels. Biochimica Et Biophysica Acta. 1808: 522-9
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