Brian Finan, Ph.D.

Affiliations: 
2011 Biochemistry Indiana University, Bloomington, Bloomington, IN, United States 
Area:
endocrinology, specifically diabetes
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Richard DiMarchi grad student 2011 Indiana University
 (Peptide targeting of nuclear hormone action leads to enhanced efficacy and safety in the treatment of the metabolic syndrome.)
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Publications

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Yang B, Gelfanov VM, Perez-Tilve D, et al. (2021) Optimization of Truncated Glucagon Peptides to Achieve Selective, High Potency, Full Antagonists. Journal of Medicinal Chemistry
Klein AB, Nicolaisen TS, Ørtenblad N, et al. (2021) Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise. Nature Communications. 12: 1041
Zhang Q, Delessa CT, Augustin R, et al. (2021) The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling. Cell Metabolism
Sachs S, Bastidas-Ponce A, Tritschler S, et al. (2020) Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission. Nature Metabolism. 2: 380
Zizzari P, He R, Falk S, et al. (2020) CB1 and GLP-1 Receptors Cross-Talk Provides New Therapies for Obesity. Diabetes
Pan J, Parlee SD, Brunel FM, et al. (2020) Optimization of Peptide Inhibitors of β-Klotho as Antagonists of Fibroblast Growth Factors 19 and 21. Acs Pharmacology & Translational Science. 3: 978-986
Sachs S, Niu L, Geyer P, et al. (2020) Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice. Diabetes, Obesity & Metabolism
Sachs S, Bastidas-Ponce A, Tritschler S, et al. (2020) Targeted pharmacological therapy restores β-cell function for diabetes remission. Nature Metabolism. 2: 192-209
Stemmer K, Finan B, DiMarchi RD, et al. (2020) Insights into incretin-based therapies for treatment of diabetic dyslipidemia. Advanced Drug Delivery Reviews
Knerr PJ, Mowery SA, Finan B, et al. (2019) Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates. Peptides. 170225
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