Alexander W. Wong, Ph.D.

2001 University of British Columbia, Vancouver, Vancouver, BC, Canada 
enzyme mechanisms, protein structure/function relationships, enzyme inhibitor design/synthesis and protein engineering
"Alexander Wong"
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Stephen G. Withers grad student 2001 UBC
 (Mechanism-based inhibitors of lysosomal glycosidases.)
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Nieman CE, Wong AW, He S, et al. (2003) Family 39 alpha-l-iduronidases and beta-D-xylosidases react through similar glycosyl-enzyme intermediates: identification of the human iduronidase nucleophile. Biochemistry. 42: 8054-65
Wong AW, He S, Grubb JH, et al. (1998) Identification of Glu-540 as the catalytic nucleophile of human beta-glucuronidase using electrospray mass spectrometry. The Journal of Biological Chemistry. 273: 34057-62
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