Youngjoo Kwon, Ph.D.

Affiliations: 
2002 University of Houston, Houston, TX, United States 
Area:
Biological NMR of Nucleic Acids and Proteins; Microarray BIOCHIP Technologies
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"Youngjoo Kwon"
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Xiaolian Gao grad student 2002 University of Houston
 (Structure determination and conformational analysis of enediyne ligand -oligonucleotide complexes.)
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Publications

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Shrestha A, Hwang SY, Kunwar S, et al. (2023) Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure-activity relationships. Bioorganic & Medicinal Chemistry. 91: 117403
Chaudhary CL, Ko S, Lee C, et al. (2022) Design, Synthesis, and Cytotoxicity and Topoisomerase I/IIα Inhibition Activity of Pyrazolo[4,3-]quinoline Derivatives. Pharmaceuticals (Basel, Switzerland). 15
Kunwar S, Hwang SY, Katila P, et al. (2022) Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 60: 128606
Jeon KH, Park S, Jang HJ, et al. (2021) AK-I-190, a New Catalytic Inhibitor of Topoisomerase II with Anti-Proliferative and Pro-Apoptotic Activity on Androgen-Negative Prostate Cancer Cells. International Journal of Molecular Sciences. 22
Hwang SY, Shrestha A, Park S, et al. (2021) Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors. European Journal of Medicinal Chemistry. 227: 113916
Kunwar S, Hwang SY, Katila P, et al. (2021) Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison. European Journal of Medicinal Chemistry. 226: 113860
Kunwar S, Hwang SY, Katila P, et al. (2021) 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships. Bioorganic Chemistry. 116: 105349
Jeon KH, Shrestha A, Jang HJ, et al. (2021) Anticancer Activity of Indeno[1,2-b]-Pyridinol Derivative as a New DNA Minor Groove Binding Catalytic Inhibitor of Topoisomerase IIα. Biomolecules & Therapeutics
Thapa Magar TB, Hee Seo S, Shrestha A, et al. (2021) Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors. Bioorganic Chemistry. 111: 104884
Kim EK, Lee KA, Hyeon DY, et al. (2020) Bacterial Nucleoside Catabolism Controls Quorum Sensing and Commensal-to-Pathogen Transition in the Drosophila Gut. Cell Host & Microbe
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