Wasfi Al-Azzam, Ph.D.

2005 University of Puerto Rico, Rio Piedras (Puerto Rico) 
Biotechnology, Biochemistry
"Wasfi Al-Azzam"
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Kai Griebenow grad student 2005 University of Puerto Rico, Rio Piedras (Puerto Rico)
 (Protein modification with poly(ethylene glycol): An approach towards protein stabilization during encapsulation and release from biocompatible polymers.)
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Stockdale G, Murphy BM, D'Antonio J, et al. (2015) Comparability of higher order structure in proteins: chemometric analysis of second-derivative amide I fourier transform infrared spectra. Journal of Pharmaceutical Sciences. 104: 25-33
Murphy BM, D'Antonio J, Manning MC, et al. (2014) Use of the amide II infrared band of proteins for secondary structure determination and comparability of higher order structure. Current Pharmaceutical Biotechnology. 15: 880-9
Nagarkar RP, Murphy BM, Yu X, et al. (2013) Characterization of protein higher order structure using vibrational circular dichroism spectroscopy. Current Pharmaceutical Biotechnology. 14: 199-208
D'antonio J, Murphy BM, Manning MC, et al. (2012) Comparability of protein therapeutics: quantitative comparison of second-derivative amide I infrared spectra. Journal of Pharmaceutical Sciences. 101: 2025-33
Geib J, Al-Azzam W. (2011) Testing for Particulates in Parenterals:GSK turns to imaging particle analysis to ensure parenteral product quality Pharmaceutical Processing. 26: 8-10
Solá RJ, Al-Azzam W, Griebenow K. (2006) Engineering of protein thermodynamic, kinetic, and colloidal stability: Chemical glycosylation with monofunctionally activated glycans Biotechnology and Bioengineering. 94: 1072-1079
Castillo B, Méndez J, Al-Azzam W, et al. (2006) On the relationship between the activity and structure of PEG-α-chymotrypsin conjugates in organic solvents Biotechnology and Bioengineering. 94: 565-574
Al-Azzam W, Pastrana EA, King B, et al. (2005) Effect of the covalent modification of horseradish peroxidase with poly(ethylene glycol) on the activity and stability upon encapsulation in polyester microspheres Journal of Pharmaceutical Sciences. 94: 1808-1819
Castellanos IJ, Al-Azzam W, Griebenow K. (2005) Effect of the covalent modification with poly(ethylene glycol) on alpha-chymotrypsin stability upon encapsulation in poly(lactic-co-glycolic) microspheres. Journal of Pharmaceutical Sciences. 94: 327-40
Castillo B, Pacheco Y, Al-Azzam W, et al. (2005) On the activity loss of hydrolases in organic solvents I. Rapid loss of activity of a variety of enzymes and formulations in a range of organic solvents Journal of Molecular Catalysis B: Enzymatic. 35: 147-153
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