Dennie S. Welch, Ph.D.

Affiliations: 
2005 University of Utah, Salt Lake City, UT 
Area:
Synthetic Organic Chemistry
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"Dennie Welch"
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Parents

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Gary Eugene Keck grad student 2005 University of Utah
 (Intramolecular Baylis -Hillman and Morita reactions and the approach to the northern hemisphere of bryostatin 1.)
David A. Evans post-doc 2005-2008 Harvard
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Publications

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Hobson AD, Xu J, Welch DS, et al. (2023) Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC). Journal of Medicinal Chemistry
Amberg A, Andaya RV, Anger LT, et al. (2018) Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses. Regulatory Toxicology and Pharmacology : Rtp
Amberg A, Beilke L, Bercu J, et al. (2016) Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses. Regulatory Toxicology and Pharmacology : Rtp
Bellizzi ME, Bhatia AV, Cullen SC, et al. (2014) Asymmetric synthesis of a TRPV1 antagonist via tert -butanesulfinamide- directed reductive amination with a chromanone Organic Process Research and Development. 18: 303-309
Evans DA, Welch DS, Speed AW, et al. (2009) An aldol-based synthesis of (+)-peloruside a, a potent microtubule stabilizing agent. Journal of the American Chemical Society. 131: 3840-1
Keck GE, Poudel YB, Welch DS, et al. (2009) Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters. Organic Letters. 11: 593-6
Evans DA, Welch DS, Speed AWH, et al. (2009) ChemInform Abstract: An Aldol-Based Synthesis of (+)-Peloruside A, a Potent Microtubule Stabilizing Agent. Cheminform. 40
Keck GE, Welch DS, Poudel YB. (2006) Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation. Tetrahedron Letters. 47: 8267-8270
Keck GE, Welch DS, Vivian PK. (2006) Synthetic studies toward the bryostatins: a substrate-controlled approach to the A-ring. Organic Letters. 8: 3667-70
Keck GE, Welch DS. (2002) Intramolecular Baylis-Hillman and morita reactions using unsaturated thiol ester substrates containing enolizable aldehydes. Organic Letters. 4: 3687-90
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