Alexandre de Lencastre, Ph.D.

Affiliations: 
2005 Columbia University, New York, NY 
Area:
Ribozymes
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"Alexandre de Lencastre"
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Anna Marie Pyle grad student 2005 Columbia
 (Exploring the structure of a group II intron using interference mapping, suppression, and photocrosslinking.)
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Publications

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de Lencastre A, Slack F. (2015) Discovery of Novel microRNAs in Aging Caenorhabditis elegans. Methods in Molecular Biology (Clifton, N.J.). 1343: 235-48
Smith-Vikos T, de Lencastre A, Inukai S, et al. (2014) MicroRNAs mediate dietary-restriction-induced longevity through PHA-4/FOXA and SKN-1/Nrf transcription factors. Current Biology : Cb. 24: 2238-46
Inukai S, de Lencastre A, Turner M, et al. (2012) Novel microRNAs differentially expressed during aging in the mouse brain. Plos One. 7: e40028
de Lencastre A, Pincus Z, Zhou K, et al. (2010) MicroRNAs both promote and antagonize longevity in C. elegans. Current Biology : Cb. 20: 2159-68
Kato M, de Lencastre A, Pincus Z, et al. (2009) Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development. Genome Biology. 10: R54
de Lencastre A, Pyle AM. (2008) Three essential and conserved regions of the group II intron are proximal to the 5'-splice site. Rna (New York, N.Y.). 14: 11-24
de Lencastre A, Hamill S, Pyle AM. (2005) A single active-site region for a group II intron. Nature Structural & Molecular Biology. 12: 626-7
Boudvillain M, de Lencastre A, Pyle AM. (2000) A tertiary interaction that links active-site domains to the 5' splice site of a group II intron. Nature. 406: 315-8
Armstrong N, de Lencastre A, Gouaux E. (1999) A new protein folding screen: application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase. Protein Science : a Publication of the Protein Society. 8: 1475-83
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