Doryen A. Bubeck, Ph.D.

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
structural biology
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"Doryen Bubeck"
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James M. Hogle grad student 2005 Harvard
 (Biochemical and structural studies exploring the mechanism of poliovirus cell entry.)
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Publications

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Couves EC, Gardner S, Voisin TB, et al. (2023) Structural basis for membrane attack complex inhibition by CD59. Nature Communications. 14: 890
Couves EC, Bubeck D. (2022) Capturing pore-forming intermediates of MACPF and binary toxin assemblies by cryoEM. Current Opinion in Structural Biology. 75: 102401
Menny A, Lukassen MV, Couves EC, et al. (2021) Structural basis of soluble membrane attack complex packaging for clearance. Nature Communications. 12: 6086
Bickel JK, Voisin TB, Tate EW, et al. (2021) How Structures of Complement Complexes Guide Therapeutic Design. Sub-Cellular Biochemistry. 96: 273-295
Barnum SR, Bubeck D, Schein TN. (2020) Soluble Membrane Attack Complex: Biochemistry and Immunobiology. Frontiers in Immunology. 11: 585108
Shah NR, Voisin TB, Parsons ES, et al. (2020) Structural basis for tuning activity and membrane specificity of bacterial cytolysins. Nature Communications. 11: 5818
McFarlane CR, Shah NR, Kabasakal BV, et al. (2019) Structural basis of light-induced redox regulation in the Calvin-Benson cycle in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America
Parsons ES, Stanley GJ, Pyne ALB, et al. (2019) Single-molecule kinetics of pore assembly by the membrane attack complex. Nature Communications. 10: 2066
Menny A, Serna M, Boyd CM, et al. (2018) CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nature Communications. 9: 5316
Boyd CM, Bubeck D. (2018) Advances in cryoEM and its impact on β-pore forming proteins. Current Opinion in Structural Biology. 52: 41-49
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