Jasper H. Yik, Ph.D.

Affiliations: 
2002 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Structure-function of Glycosaminoglycan Receptors and Hyaluronic Acid Synthases and their roles in human diseases
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"Jasper Yik"
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Paul H. Weigel grad student 2002 University of Oklahoma Health Sciences Center
 (Palmitoylation of the asialoglycoprotein receptor.)
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Publications

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Hong E, Yik J, Amanatullah DF, et al. (2013) c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells Cartilage. 4: 177-186
Kumari R, Li H, Haudenschild DR, et al. (2012) The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Carcinogenesis. 33: 2076-83
Amanatullah DF, Lu J, Hecht J, et al. (2012) Identification of a 3Kbp mechanoresponsive promoter region in the human cartilage oligomeric matrix protein gene Tissue Engineering - Part A. 18: 1882-1889
Christiansen BA, Anderson MJ, Lee CA, et al. (2012) Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 20: 773-82
Haudenschild DR, Hong E, Yik JH, et al. (2011) Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein. The Journal of Biological Chemistry. 286: 43250-8
Yang Z, Yik JH, Chen R, et al. (2005) Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Molecular Cell. 19: 535-45
Yik JH, Chen R, Pezda AC, et al. (2005) Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. The Journal of Biological Chemistry. 280: 16368-76
Yik JH, Chen R, Pezda AC, et al. (2004) A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. Molecular and Cellular Biology. 24: 5094-105
Yik JH, Chen R, Nishimura R, et al. (2003) Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Molecular Cell. 12: 971-82
Yik JH, Weigel PH. (2002) The position of cysteine relative to the transmembrane domain is critical for palmitoylation of H1, the major subunit of the human asialoglycoprotein receptor. The Journal of Biological Chemistry. 277: 47305-12
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