Paul T. Wilder, Ph.D.

Affiliations: 
2004 University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
structure and function of S100B, a growth factor in the brain and skin
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"Paul Wilder"
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David J. Weber grad student 2004 University of Maryland Medical School
 (S100B regulation of p53 phosphorylation by PKC(alpha) and structural characterization of zinc(2+)-binding to calcium(2+)-S100B.)
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Publications

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Chen L, Chan AM, Wilder PT, et al. (2022) 1-Sulfonylated 1,2,3,4-tetrahydroquinoline-6-carboxylic acids as simple, readily-accessible MCL-1 inhibitors. Drug Development Research
Young BD, Varney KM, Wilder PT, et al. (2021) Physiologically Relevant Free Ca Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6. Journal of Molecular Biology. 433: 167272
Alasady MJ, Terry AR, Pierce AD, et al. (2021) The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling. Plos One. 16: e0256238
Conlon IL, Drennen B, Lanning ME, et al. (2020) Rationally Designed Polypharmacology: α-Helix Mimetics as Dual Inhibitors of the Oncoproteins Mcl-1 and HDM2. Chemmedchem
Varney KM, Wilder PT, Godoy-Ruiz R, et al. (2020) Correction to: H, C, and N resonance assignments of human calmodulin bound to a peptide derived from the STRA6 vitamin A transporter (CaMBP2). Biomolecular Nmr Assignments
Xu X, Godoy-Ruiz R, Adipietro KA, et al. (2020) Structure of the cell-binding component of the binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences of the United States of America
Costabile BK, Chen Y, Kim J, et al. (2020) Investigating the Mechanism of STRA6-Mediated Cellular Retinol Uptake Biophysical Journal. 118: 93a
Coburn K, Solano-Gonzalez E, Roth B, et al. (2020) Investigation of the Impact of Post-Translational Modifications of HNRNP A18 on Small Molecule Inhibitors Biophysical Journal. 118: 49a
Donohue E, Khorsand S, Mercado G, et al. (2019) Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder. Proceedings of the National Academy of Sciences of the United States of America
Bester SM, Adipietro KA, Funk VL, et al. (2019) The structural and biochemical impact of monomerizing human acetylcholinesterase. Protein Science : a Publication of the Protein Society
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