Justine A. Melo

Affiliations: 
2003 University of California, San Francisco, San Francisco, CA 
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Parents

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David Toczyski grad student 2003 UCSF
 (Detection of DNA damage by the DNA damage checkpoint in Saccharomyces cerevisiae.)
Gary Ruvkun post-doc 2004-
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Publications

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Melo JA, Ruvkun G. (2012) Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell. 149: 452-66
Soukas AA, Kane EA, Carr CE, et al. (2009) Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes & Development. 23: 496-511
Bonilla CY, Melo JA, Toczyski DP. (2008) Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Molecular Cell. 30: 267-76
Kaye JA, Melo JA, Cheung SK, et al. (2004) DNA breaks promote genomic instability by impeding proper chromosome segregation Current Biology. 14: 2096-2106
Melo J, Toczyski D. (2002) A unified view of the DNA-damage checkpoint. Current Opinion in Cell Biology. 14: 237-45
Melo JA, Cohen J, Toczyski DP. (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes & Development. 15: 2809-21
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