David M. Sabatini
Affiliations: | Biology | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
regulators of growthWebsite:
https://biology.mit.edu/people/david_sabatiniGoogle:
"David Sabatini"Bio:
http://sabatinilab.wi.mit.edu/
Mean distance: 9.77 (cluster 25) | S | N | B | C | P |
Cross-listing: Cell Biology Tree
Parents
Sign in to add mentor| Solomon H. Snyder | grad student | 1997 | Johns Hopkins (Neurotree) | |
| (Control of translation by a novel, rapamycin-sensitive signaling pathway) | ||||
Children
Sign in to add trainee| Nora Kory | grad student | (Cell Biology Tree) | |
| Mathieu Laplante | grad student | (Neurotree) | |
| Monther Abu-Remaileh | post-doc | Whitehead Institute (MIT), HHMI (Neurotree) | |
| Anne E. Carpenter | post-doc | Whitehead Institute for Biomedical Research (MIT) (Cell Biology Tree) | |
| Ellen R. Edenberg | post-doc | ||
| Stephen C. Wilson | post-doc | MIT (ID Tree) | |
| Kris Wood | post-doc | ||
| Kivanc birsoy | post-doc | 2010- | Whitehead Institute (Neurotree) |
| Michael E. Pacold | post-doc | 2010- | Whitehead Institute (MIT) |
| Kuang Shen | post-doc | 2013- | Whitehead Institute (MIT), HHMI |
| Raghu R. Chivukula | post-doc | 2018- | Whitehead Institute (GenetiTree) |
| Dudley W. Lamming | post-doc | 2008-2013 | MIT (Microtree) |
| Omer H. Yilmaz | post-doc | 2011-2014 | (Neurotree) |
| Kacper B. Rogala | post-doc | 2016-2021 | MIT (Crystallography Tree) |
Collaborators
Sign in to add collaborator| Heide Christine Patterson | collaborator | 2011- | Whitehead Institute for Biomedical Research (MIT) (Cell Biology Tree) |
BETA: Related publications
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Publications
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| Pena IA, Shi JS, Chang SM, et al. (2025) SLC25A38 is required for mitochondrial pyridoxal 5'-phosphate (PLP) accumulation. Nature Communications. 16: 978 |
| Valenstein ML, Lalgudi PV, Kedir JF, et al. (2025) Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation. Nature. 637: E11-E14 |
| Chen WW, Pacold ME, Sabatini DM, et al. (2024) Technologies for Decoding Cancer Metabolism with Spatial Resolution. Cold Spring Harbor Perspectives in Medicine |
| Valenstein ML, Lalgudi PV, Gu X, et al. (2024) Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway. Proceedings of the National Academy of Sciences of the United States of America. 121: e2322755121 |
| Yu Y, Gao SM, Guan Y, et al. (2024) Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity. Elife. 13 |
| Laqtom NN, Dong W, Medoh UN, et al. (2022) CLN3 is required for the clearance of glycerophosphodiesters from lysosomes. Nature |
| Alvarez SW, Sviderskiy VO, Terzi EM, et al. (2022) Author Correction: NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. Nature. 609: E12 |
| Valenstein ML, Rogala KB, Lalgudi PV, et al. (2022) Structure of the nutrient-sensing hub GATOR2. Nature. 607: 610-616 |
| Kanarek N, Keys HR, Cantor JR, et al. (2022) Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity. Nature |
| Schlingmann KP, Jouret F, Shen K, et al. (2021) mTOR-Activating Mutations in RRAGD are Causative for Kidney Tubulopathy and Cardiomyopathy. Journal of the American Society of Nephrology : Jasn |