David M. Sabatini

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
regulators of growth
Website:
https://biology.mit.edu/people/david_sabatini
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"David Sabatini"
Bio:

http://sabatinilab.wi.mit.edu/

Mean distance: 9.77 (cluster 25)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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Solomon H. Snyder grad student 1997 Johns Hopkins (Neurotree)
 (Control of translation by a novel, rapamycin-sensitive signaling pathway)

Children

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Monther Abu-Remaileh post-doc Whitehead Institute (MIT), HHMI (Neurotree)
Anne E. Carpenter post-doc Whitehead Institute for Biomedical Research (MIT) (Cell Biology Tree)
Ellen R. Edenberg post-doc
Stephen C. Wilson post-doc MIT (ID Tree)
Kris Wood post-doc
Kivanc birsoy post-doc 2010- Whitehead Institute (Neurotree)
Michael E. Pacold post-doc 2010- Whitehead Institute (MIT)
Kuang Shen post-doc 2013- Whitehead Institute (MIT), HHMI
Kacper B. Rogala post-doc 2016- Whitehead Institute (MIT), HHMI (Crystallography Tree)
Raghu R. Chivukula post-doc 2018- Whitehead Institute (GenetiTree)
Omer H. Yilmaz post-doc 2011-2014 (Neurotree)
BETA: Related publications

Publications

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Condon KJ, Sabatini DM. (2019) Nutrient regulation of mTORC1 at a glance. Journal of Cell Science. 132
Shen K, Rogala KB, Chou HT, et al. (2019) Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex. Cell
Anandapadamanaban M, Masson GR, Perisic O, et al. (2019) Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science (New York, N.Y.). 366: 203-210
Rogala KB, Gu X, Kedir JF, et al. (2019) Structural basis for the docking of mTORC1 on the lysosomal surface. Science (New York, N.Y.)
Pentinmikko N, Iqbal S, Mana M, et al. (2019) Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Nature
Kikani CK, Wu X, Fogarty S, et al. (2019) Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program. Proceedings of the National Academy of Sciences of the United States of America
Li Y, Muffat J, Omer Javed A, et al. (2019) Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America
Garcia-Bermudez J, Baudrier L, Bayraktar EC, et al. (2019) Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature
Shen K, Valenstein ML, Gu X, et al. (2019) Arg78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases. The Journal of Biological Chemistry
Adelmann CH, Wang T, Sabatini DM, et al. (2019) Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines. Methods in Molecular Biology (Clifton, N.J.). 1907: 125-136
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