Ryan T. Cirz, Ph.D.

Affiliations: 
2007 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"Ryan Cirz"
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Publications

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Laponogov I, Pan XS, Veselkov DA, et al. (2016) Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones. Open Biology. 6
Heine HS, Chuvala L, Riggins R, et al. (2016) Natural history of francisella tularensis in aerosol-challenged BALB/c Mice Antimicrobial Agents and Chemotherapy. 60: 1834-1840
Drusano GL, Liu W, Fikes S, et al. (2014) Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model. The Journal of Infectious Diseases. 210: 1319-24
Heine HS, Chuvala L, Riggins R, et al. (2013) Natural history of Yersinia pestis pneumonia in aerosol-challenged BALB/c mice. Antimicrobial Agents and Chemotherapy. 57: 2010-5
Roberts TC, Smith PA, Cirz RT, et al. (2007) Structural and initial biological analysis of synthetic arylomycin A2. Journal of the American Chemical Society. 129: 15830-8
Cirz RT, Romesberg FE. (2007) Controlling mutation: intervening in evolution as a therapeutic strategy. Critical Reviews in Biochemistry and Molecular Biology. 42: 341-54
Cirz RT, Jones MB, Gingles NA, et al. (2007) Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin. Journal of Bacteriology. 189: 531-9
Cirz RT, O'Neill BM, Hammond JA, et al. (2006) Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Journal of Bacteriology. 188: 7101-10
Cirz RT, Gingles N, Romesberg FE. (2006) Side effects may include evolution. Nature Medicine. 12: 890-1
Cirz RT, Romesberg FE. (2006) Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria. Antimicrobial Agents and Chemotherapy. 50: 220-5
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